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09-07-2006, 09:23 AM
Home Preparation Procedure for Emergency Administration of Potassium Iodide Tablets to Infants and Small Children
INTRODUCTION
In the event of accidental release (or nuclear explosion, terrorist nuclear weapon) of radioactive iodine into the atmosphere, potassium iodide (KI) is recommended for use as an aid to other emergency measures, such as evacuation and food control measures. When used correctly, potassium iodide can prevent or reduce the amount of radioactive iodine taken up by the thyroid gland. The government stockpiles potassium iodide for emergency uses, such as in the event of an unexpected release of radioactive iodide.
Potassium iodide (KI) is stockpiled as tablets because tablets are easier to store; however, infants and small children cannot swallow tablets. In an emergency such as an unexpected release of radioactive iodine, the potassium iodide tablets may need to be given to infants and children by their parents or caregivers. Since potassium iodide dissolved in water may be too salty to drink, the Food and Drug Administration (FDA) is providing parents or caregivers with instructions on how to mix the potassium iodide tablets with a food or a drink to disguise the taste so infants and small children will take the medicine in an emergency. To see what worked best to disguise the taste of potassium iodide, FDA asked adults to taste the following six mixtures of potassium iodide and drinks.
Water
Low fat white milk
Low fat chocolate milk
Orange juice
Flat Soda (For example, cola)
Raspberry syrup
The mixture of potassium iodide with raspberry syrup disguises the taste of potassium iodide best. The mixtures of potassium iodide with low fat chocolate milk, orange juice, and flat soda (for example, cola) generally have an acceptable taste. Low fat white milk and water did not hide the salty taste of potassium iodide.
INGREDIENTS AND SUPPLIES NEEDED TO PREPARE POTASSIUM IODIDE (KI) TABLETS
Potassium iodide (KI) 130 mg tablet
Metal teaspoon
Small bowl
One of the drinks from the list above or infant formula.
PREPARATION FOR 130 MG POTASSIUM IODIDE TABLET
1. Grinding the potassium iodide tablet into powder
Put one 130mg potassium iodide tablet into a small bowl and grind it into a fine powder using the back of the metal teaspoon against the inside of the bowl. The powder should not have any large pieces.
2. Mixing potassium iodide powder into a drink
Add four teaspoonfuls of water to the potassium iodide powder in the small bowl. Use a spoon to mix them together until the potassium iodide powder is dissolved in the water.
3. Mix drink of choice with potassium iodide powder and water solution
Add four teaspoonfuls of drink to the potassium iodide powder and water mixture described in Step 2.
The amount of potassium iodide in the drink is 16.25 mg per teaspoon. The number of teaspoonfuls of the drink to give your child depends on your child's age. There is a chart at the end of these directions to tell you how much to give your child.
The potassium iodide in any of the six drinks listed above and infant formulas will keep for up to seven days in the refrigerator. FDA recommends that the potassium iodide drink mixtures be prepared weekly; unused portions should be discarded.
ADMINISTRATION
FDA recommends doses for potassium iodide based on age, predicted thyroid exposure to radioiodines, and -for women -- whether the woman is pregnant or nursing (see Table 1). Adults over 18 years of age and pregnant or lactating women should take the potassium iodide 130-mg tablet. Infants, children, and adolescents through 18 years of age should take potassium iodide in a drink prepared according to the procedure described above. Table 2 shows how many teaspoonfuls of potassium iodide mixture to give to an adolescent, child, or infant. The dose of potassium iodide should be taken once a day until a risk of significant exposure to radioiodines no longer exists.
If you are:
And your predicted Thyroid Exposure is
Then you should take: Number of 130 mg tablets
An adult over the age of 40
Equal to or greater than 500 centi-grays (cGy)
a 130 mg dose of potassium Iodide (KI)
1
An adult between the ages of 18 and 40
Equal to or greater than 10 cGy
A pregnant or lactating woman
Equal to or greater than 5cGy
Table 2. Recommended doses of KI for adolescents, children, and infants with predicted thyroid radioactivity exposures equal to or greater than 5 cGy1, using 130 mg tablet preparations.
If your child is:
Give your child this amount of Potassium Iodide (KI) *
An adolescent between 12 and 18 years old**
4 teaspoonfuls (NOT tablespoonfuls)
65 mg of potassium iodide (KI)
Between 4 and 12 years old
4 teaspoonfuls (NOT tablespoonfuls)
65 mg of potassium iodide (KI)
Over 1 month through 3 years
2 teaspoonfuls (NOT tablespoonfuls)
32.5 mg of potassium iodide (KI)
An infant from birth through 1 month
1 teaspoonful (NOT a tablespoonful)
16.25 mg of potassium iodide (KI)
* This is the amount to give your child for one dose. You should give your child one dose each day.
** Adolescents approaching adult size [equal to or greater than 154 pounds (70 kg)] should receive the full adult dose (130 mg tablet or 8 teaspoonfuls of KI mixture each day.
INTRODUCTION
In the event of accidental release (or nuclear explosion, terrorist nuclear weapon) of radioactive iodine into the atmosphere, potassium iodide (KI) is recommended for use as an aid to other emergency measures, such as evacuation and food control measures. When used correctly, potassium iodide can prevent or reduce the amount of radioactive iodine taken up by the thyroid gland. The government stockpiles potassium iodide for emergency uses, such as in the event of an unexpected release of radioactive iodide.
Potassium iodide (KI) is stockpiled as tablets because tablets are easier to store; however, infants and small children cannot swallow tablets. In an emergency such as an unexpected release of radioactive iodine, the potassium iodide tablets may need to be given to infants and children by their parents or caregivers. Since potassium iodide dissolved in water may be too salty to drink, the Food and Drug Administration (FDA) is providing parents or caregivers with instructions on how to mix the potassium iodide tablets with a food or a drink to disguise the taste so infants and small children will take the medicine in an emergency. To see what worked best to disguise the taste of potassium iodide, FDA asked adults to taste the following six mixtures of potassium iodide and drinks.
Water
Low fat white milk
Low fat chocolate milk
Orange juice
Flat Soda (For example, cola)
Raspberry syrup
The mixture of potassium iodide with raspberry syrup disguises the taste of potassium iodide best. The mixtures of potassium iodide with low fat chocolate milk, orange juice, and flat soda (for example, cola) generally have an acceptable taste. Low fat white milk and water did not hide the salty taste of potassium iodide.
INGREDIENTS AND SUPPLIES NEEDED TO PREPARE POTASSIUM IODIDE (KI) TABLETS
Potassium iodide (KI) 130 mg tablet
Metal teaspoon
Small bowl
One of the drinks from the list above or infant formula.
PREPARATION FOR 130 MG POTASSIUM IODIDE TABLET
1. Grinding the potassium iodide tablet into powder
Put one 130mg potassium iodide tablet into a small bowl and grind it into a fine powder using the back of the metal teaspoon against the inside of the bowl. The powder should not have any large pieces.
2. Mixing potassium iodide powder into a drink
Add four teaspoonfuls of water to the potassium iodide powder in the small bowl. Use a spoon to mix them together until the potassium iodide powder is dissolved in the water.
3. Mix drink of choice with potassium iodide powder and water solution
Add four teaspoonfuls of drink to the potassium iodide powder and water mixture described in Step 2.
The amount of potassium iodide in the drink is 16.25 mg per teaspoon. The number of teaspoonfuls of the drink to give your child depends on your child's age. There is a chart at the end of these directions to tell you how much to give your child.
The potassium iodide in any of the six drinks listed above and infant formulas will keep for up to seven days in the refrigerator. FDA recommends that the potassium iodide drink mixtures be prepared weekly; unused portions should be discarded.
ADMINISTRATION
FDA recommends doses for potassium iodide based on age, predicted thyroid exposure to radioiodines, and -for women -- whether the woman is pregnant or nursing (see Table 1). Adults over 18 years of age and pregnant or lactating women should take the potassium iodide 130-mg tablet. Infants, children, and adolescents through 18 years of age should take potassium iodide in a drink prepared according to the procedure described above. Table 2 shows how many teaspoonfuls of potassium iodide mixture to give to an adolescent, child, or infant. The dose of potassium iodide should be taken once a day until a risk of significant exposure to radioiodines no longer exists.
If you are:
And your predicted Thyroid Exposure is
Then you should take: Number of 130 mg tablets
An adult over the age of 40
Equal to or greater than 500 centi-grays (cGy)
a 130 mg dose of potassium Iodide (KI)
1
An adult between the ages of 18 and 40
Equal to or greater than 10 cGy
A pregnant or lactating woman
Equal to or greater than 5cGy
Table 2. Recommended doses of KI for adolescents, children, and infants with predicted thyroid radioactivity exposures equal to or greater than 5 cGy1, using 130 mg tablet preparations.
If your child is:
Give your child this amount of Potassium Iodide (KI) *
An adolescent between 12 and 18 years old**
4 teaspoonfuls (NOT tablespoonfuls)
65 mg of potassium iodide (KI)
Between 4 and 12 years old
4 teaspoonfuls (NOT tablespoonfuls)
65 mg of potassium iodide (KI)
Over 1 month through 3 years
2 teaspoonfuls (NOT tablespoonfuls)
32.5 mg of potassium iodide (KI)
An infant from birth through 1 month
1 teaspoonful (NOT a tablespoonful)
16.25 mg of potassium iodide (KI)
* This is the amount to give your child for one dose. You should give your child one dose each day.
** Adolescents approaching adult size [equal to or greater than 154 pounds (70 kg)] should receive the full adult dose (130 mg tablet or 8 teaspoonfuls of KI mixture each day.